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SMILES: C(CCN1CCc2ccccc2C1)CCc1cc(CCCCCN2CCc3ccccc3C2)c(CCCCCN2CCc3ccccc3C2)cc1CCCCCN1CCc2ccccc2C1

InChI Key: InChIKey=KTHOUICBVFUICX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334473   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-6


(Rattus norvegicus)		BDBM50334473
PNG
(1,2,4,5-tetrakis(5-(3,4-dihydroisoquinolin-2(1H)-y...)
Show SMILES C(CCN1CCc2ccccc2C1)CCc1cc(CCCCCN2CCc3ccccc3C2)c(CCCCCN2CCc3ccccc3C2)cc1CCCCCN1CCc2ccccc2C1
Show InChI InChI=1S/C62H82N4/c1(17-37-63-41-33-51-21-9-13-29-59(51)47-63)5-25-55-45-57(27-7-3-19-39-65-43-35-53-23-11-15-31-61(53)49-65)58(28-8-4-20-40-66-44-36-54-24-12-16-32-62(54)50-66)46-56(55)26-6-2-18-38-64-42-34-52-22-10-14-30-60(52)48-64/h9-16,21-24,29-32,45-46H,1-8,17-20,25-28,33-44,47-50H2
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 205n/an/an/an/an/an/a



University of Kentucky

Curated by ChEMBL


Assay Description
Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine release

Bioorg Med Chem Lett 21: 88-91 (2010)


Article DOI: 10.1016/j.bmcl.2010.11.070
BindingDB Entry DOI: 10.7270/Q2VT1SDX
More data for this
Ligand-Target Pair