BDBM50334566 CHEMBL1641944::N3-(1-Adamantyl)-1-butyl-4-oxo-6-phenyl-1,4-dihydropyridine-3-carboxamide

SMILES: CCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1

InChI Key: InChIKey=FGWRYMHPXJPSPO-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50334566 (CHEMBL1641944 | N3-(1-Adamantyl)-1-butyl-4-oxo-6-p...) Show SMILES CCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1 |TLB:13:14:12.11.17:18,THB:15:14:11:17.16.18,15:16:13.14.19:11,13:12:14.19.15:18| Show InChI InChI=1S/C26H32N2O2/c1-2-3-9-28-17-22(24(29)13-23(28)21-7-5-4-6-8-21)25(30)27-26-14-18-10-19(15-26)12-20(11-18)16-26/h4-8,13,17-20H,2-3,9-12,14-16H2,1H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite£? Lille-Nord de France Curated by ChEMBL					Assay Description Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells after 1 hr				J Med Chem 53: 7918-31 (2010) Article DOI: 10.1021/jm100286k BindingDB Entry DOI: 10.7270/Q2BR8SFP
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334566 (CHEMBL1641944 | N3-(1-Adamantyl)-1-butyl-4-oxo-6-p...) Show SMILES CCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1 |TLB:13:14:12.11.17:18,THB:15:14:11:17.16.18,15:16:13.14.19:11,13:12:14.19.15:18| Show InChI InChI=1S/C26H32N2O2/c1-2-3-9-28-17-22(24(29)13-23(28)21-7-5-4-6-8-21)25(30)27-26-14-18-10-19(15-26)12-20(11-18)16-26/h4-8,13,17-20H,2-3,9-12,14-16H2,1H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite£? Lille-Nord de France Curated by ChEMBL					Assay Description Displacement of [3H]-SR141716A from human CB1 receptor expressed in CHO cells after 1 hr				J Med Chem 53: 7918-31 (2010) Article DOI: 10.1021/jm100286k BindingDB Entry DOI: 10.7270/Q2BR8SFP
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50334566 (CHEMBL1641944 | N3-(1-Adamantyl)-1-butyl-4-oxo-6-p...) Show SMILES CCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1 |TLB:13:14:12.11.17:18,THB:15:14:11:17.16.18,15:16:13.14.19:11,13:12:14.19.15:18| Show InChI InChI=1S/C26H32N2O2/c1-2-3-9-28-17-22(24(29)13-23(28)21-7-5-4-6-8-21)25(30)27-26-14-18-10-19(15-26)12-20(11-18)16-26/h4-8,13,17-20H,2-3,9-12,14-16H2,1H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.40	n/a	n/a	n/a	n/a
Universite£? Lille-Nord de France Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS binding				J Med Chem 53: 7918-31 (2010) Article DOI: 10.1021/jm100286k BindingDB Entry DOI: 10.7270/Q2BR8SFP
					More data for this Ligand-Target Pair