BDBM50334666 7-Methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline::CHEMBL1642582

SMILES: COc1cccc2c3cc(C)nn3c(CCc3nc(cn3C)-c3ccccc3)nc12

InChI Key: InChIKey=RPAGXILTZTWVMX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334666   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50334666 (7-Methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imid...) Show SMILES COc1cccc2c3cc(C)nn3c(CCc3nc(cn3C)-c3ccccc3)nc12 Show InChI InChI=1S/C24H23N5O/c1-16-14-20-18-10-7-11-21(30-3)24(18)26-23(29(20)27-16)13-12-22-25-19(15-28(22)2)17-8-5-4-6-9-17/h4-11,14-15H,12-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Sassari Curated by ChEMBL					Assay Description Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assay				Bioorg Med Chem 19: 642-9 (2011) Article DOI: 10.1016/j.bmc.2010.10.038 BindingDB Entry DOI: 10.7270/Q2TT4R73
					More data for this Ligand-Target Pair