Found 8 hits for monomerid = 50334919 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 132 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5HT transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086 BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 601 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Inhibition of human recombinant norepinephrine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086 BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Inhibition of human recombinant dopamine transporter |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086 BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086 BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Inhibition of CYP2C19 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086 BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Inhibition of CYP2D6 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086 BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Inhibition of CYP3A4 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086 BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50334919
((R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)Show SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12 |r| Show InChI InChI=1S/C16H16Cl2N2/c1-19-15-8-9-20(16-5-3-2-4-12(15)16)11-6-7-13(17)14(18)10-11/h2-7,10,15,19H,8-9H2,1H3/t15-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Inhibition of CYP2C9 |
Bioorg Med Chem Lett 21: 520-3 (2010)
Article DOI: 10.1016/j.bmcl.2010.10.086 BindingDB Entry DOI: 10.7270/Q2DJ5FWS |
More data for this Ligand-Target Pair | |