BDBM50334998 3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazole::CHEMBL1649949

SMILES: Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1

InChI Key: InChIKey=LPJNRJXWXMNHIA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50334998 (3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazol...) Show SMILES Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1 Show InChI InChI=1S/C21H17N3/c1-16-22-23-21(24(16)20-10-6-3-7-11-20)19-14-12-18(13-15-19)17-8-4-2-5-9-17/h2-15H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...				Bioorg Med Chem Lett 21: 5684-7 (2011) Article DOI: 10.1016/j.bmcl.2011.08.038 BindingDB Entry DOI: 10.7270/Q2TB179T
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (attus norvegicus (Rat))	BDBM50334998 (3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazol...) Show SMILES Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1 Show InChI InChI=1S/C21H17N3/c1-16-22-23-21(24(16)20-10-6-3-7-11-20)19-14-12-18(13-15-19)17-8-4-2-5-9-17/h2-15H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cells				J Med Chem 54: 387-91 (2011) Article DOI: 10.1021/jm101031u BindingDB Entry DOI: 10.7270/Q2H9965H
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Rattus norvegicus)	BDBM50334998 (3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazol...) Show SMILES Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1 Show InChI InChI=1S/C21H17N3/c1-16-22-23-21(24(16)20-10-6-3-7-11-20)19-14-12-18(13-15-19)17-8-4-2-5-9-17/h2-15H,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cells				J Med Chem 54: 387-91 (2011) Article DOI: 10.1021/jm101031u BindingDB Entry DOI: 10.7270/Q2H9965H
					More data for this Ligand-Target Pair