BDBM50335069 2-Amino-5-(2-naphthyl)-4-[2-(5-phosphono)furanyl]thiazole::CHEMBL1650209

SMILES: Nc1nc(-c2ccc(o2)P(O)(O)=O)c(s1)-c1ccc2ccccc2c1

InChI Key: InChIKey=NEWRPBLPJFLNQF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase 1 (FBPase) (Homo sapiens (Human))	BDBM50335069 (2-Amino-5-(2-naphthyl)-4-[2-(5-phosphono)furanyl]t...) Show SMILES Nc1nc(-c2ccc(o2)P(O)(O)=O)c(s1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C17H13N2O4PS/c18-17-19-15(13-7-8-14(23-13)24(20,21)22)16(25-17)12-6-5-10-3-1-2-4-11(10)9-12/h1-9H,(H2,18,19)(H2,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Metabasis Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human liver FBP				J Med Chem 54: 153-65 (2011) Article DOI: 10.1021/jm101035x BindingDB Entry DOI: 10.7270/Q2CN74WJ
					More data for this Ligand-Target Pair