BDBM50335197 3-Acetyl-7-para-tolyl-2H-chromen-2-one::CHEMBL1650700

SMILES: CC(=O)c1cc2ccc(cc2oc1=O)-c1ccc(C)cc1

InChI Key: InChIKey=RJZLPTVYFLCCEJ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50335197 (3-Acetyl-7-para-tolyl-2H-chromen-2-one | CHEMBL165...) Show SMILES CC(=O)c1cc2ccc(cc2oc1=O)-c1ccc(C)cc1 Show InChI InChI=1S/C18H14O3/c1-11-3-5-13(6-4-11)14-7-8-15-9-16(12(2)19)18(20)21-17(15)10-14/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	585	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by competitive inhibition assay in presence of...				J Med Chem 54: 248-61 (2011) Article DOI: 10.1021/jm101104z BindingDB Entry DOI: 10.7270/Q2QV3NG1
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50335197 (3-Acetyl-7-para-tolyl-2H-chromen-2-one | CHEMBL165...) Show SMILES CC(=O)c1cc2ccc(cc2oc1=O)-c1ccc(C)cc1 Show InChI InChI=1S/C18H14O3/c1-11-3-5-13(6-4-11)14-7-8-15-9-16(12(2)19)18(20)21-17(15)10-14/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by scintillation counting in presence of bacte...				J Med Chem 54: 248-61 (2011) Article DOI: 10.1021/jm101104z BindingDB Entry DOI: 10.7270/Q2QV3NG1
					More data for this Ligand-Target Pair