BDBM50335199 3-Acetyl-7-(4-hydroxyphenyl)-2H-chromen-2-one::CHEMBL1650702

SMILES: CC(=O)c1cc2ccc(cc2oc1=O)-c1ccc(O)cc1

InChI Key: InChIKey=ZQKQNWVNRGJPJK-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50335199 (3-Acetyl-7-(4-hydroxyphenyl)-2H-chromen-2-one | CH...) Show SMILES CC(=O)c1cc2ccc(cc2oc1=O)-c1ccc(O)cc1 Show InChI InChI=1S/C17H12O4/c1-10(18)15-8-13-3-2-12(9-16(13)21-17(15)20)11-4-6-14(19)7-5-11/h2-9,19H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	143	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by competitive inhibition assay in presence of...				J Med Chem 54: 248-61 (2011) Article DOI: 10.1021/jm101104z BindingDB Entry DOI: 10.7270/Q2QV3NG1
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50335199 (3-Acetyl-7-(4-hydroxyphenyl)-2H-chromen-2-one | CH...) Show SMILES CC(=O)c1cc2ccc(cc2oc1=O)-c1ccc(O)cc1 Show InChI InChI=1S/C17H12O4/c1-10(18)15-8-13-3-2-12(9-16(13)21-17(15)20)11-4-6-14(19)7-5-11/h2-9,19H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by scintillation counting in presence of bacte...				J Med Chem 54: 248-61 (2011) Article DOI: 10.1021/jm101104z BindingDB Entry DOI: 10.7270/Q2QV3NG1
					More data for this Ligand-Target Pair