BDBM50335320 4-(5-Methyl-1H-pyrazol-3-ylamino)-2-(2-methylthiazol-4-ylmethyl)-2H-phthalazin-1-one::CHEMBL1651487

SMILES: Cc1cc(Nc2nn(Cc3csc(C)n3)c(=O)c3ccccc23)[nH]n1

InChI Key: InChIKey=NXDNERZXWCKICJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50335320 (4-(5-Methyl-1H-pyrazol-3-ylamino)-2-(2-methylthiaz...) Show SMILES Cc1cc(Nc2nn(Cc3csc(C)n3)c(=O)c3ccccc23)[nH]n1 Show InChI InChI=1S/C17H16N6OS/c1-10-7-15(21-20-10)19-16-13-5-3-4-6-14(13)17(24)23(22-16)8-12-9-25-11(2)18-12/h3-7,9H,8H2,1-2H3,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Inhibition of Aurora A by ELISA				J Med Chem 54: 312-9 (2011) Article DOI: 10.1021/jm101346r BindingDB Entry DOI: 10.7270/Q29P32MB
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50335320 (4-(5-Methyl-1H-pyrazol-3-ylamino)-2-(2-methylthiaz...) Show SMILES Cc1cc(Nc2nn(Cc3csc(C)n3)c(=O)c3ccccc23)[nH]n1 Show InChI InChI=1S/C17H16N6OS/c1-10-7-15(21-20-10)19-16-13-5-3-4-6-14(13)17(24)23(22-16)8-12-9-25-11(2)18-12/h3-7,9H,8H2,1-2H3,(H2,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Inhibition of Aurora B by ELISA				J Med Chem 54: 312-9 (2011) Article DOI: 10.1021/jm101346r BindingDB Entry DOI: 10.7270/Q29P32MB
					More data for this Ligand-Target Pair