BDBM50335335 2-Benzyl-4-(5-methyl-1H-pyrazol-3-ylamino)-2H-phthalazin-1-one::CHEMBL1651461

SMILES: Cc1cc(Nc2nn(Cc3ccccc3)c(=O)c3ccccc23)[nH]n1

InChI Key: InChIKey=PPOHPGMKFGMFKE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335335   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50335335 (2-Benzyl-4-(5-methyl-1H-pyrazol-3-ylamino)-2H-phth...) Show SMILES Cc1cc(Nc2nn(Cc3ccccc3)c(=O)c3ccccc23)[nH]n1 Show InChI InChI=1S/C19H17N5O/c1-13-11-17(22-21-13)20-18-15-9-5-6-10-16(15)19(25)24(23-18)12-14-7-3-2-4-8-14/h2-11H,12H2,1H3,(H2,20,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Inhibition of Aurora A by ELISA				J Med Chem 54: 312-9 (2011) Article DOI: 10.1021/jm101346r BindingDB Entry DOI: 10.7270/Q29P32MB
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50335335 (2-Benzyl-4-(5-methyl-1H-pyrazol-3-ylamino)-2H-phth...) Show SMILES Cc1cc(Nc2nn(Cc3ccccc3)c(=O)c3ccccc23)[nH]n1 Show InChI InChI=1S/C19H17N5O/c1-13-11-17(22-21-13)20-18-15-9-5-6-10-16(15)19(25)24(23-18)12-14-7-3-2-4-8-14/h2-11H,12H2,1H3,(H2,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Inhibition of Aurora B by ELISA				J Med Chem 54: 312-9 (2011) Article DOI: 10.1021/jm101346r BindingDB Entry DOI: 10.7270/Q29P32MB
					More data for this Ligand-Target Pair