BDBM50335341 4-(1H-pyrazol-3-ylamino)-2-p-tolylphthalazin-1(2H)-one::CHEMBL1651474

SMILES: Cc1ccc(cc1)-n1nc(Nc2ccn[nH]2)c2ccccc2c1=O

InChI Key: InChIKey=CYIVQMRMONWPKP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50335341 (4-(1H-pyrazol-3-ylamino)-2-p-tolylphthalazin-1(2H)...) Show SMILES Cc1ccc(cc1)-n1nc(Nc2ccn[nH]2)c2ccccc2c1=O Show InChI InChI=1S/C18H15N5O/c1-12-6-8-13(9-7-12)23-18(24)15-5-3-2-4-14(15)17(22-23)20-16-10-11-19-21-16/h2-11H,1H3,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Inhibition of Aurora A by ELISA				J Med Chem 54: 312-9 (2011) Article DOI: 10.1021/jm101346r BindingDB Entry DOI: 10.7270/Q29P32MB
					More data for this Ligand-Target Pair