Found 3 hits for monomerid = 50335554 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
DNA polymerase alpha catalytic subunit
(Homo sapiens (Human)) | BDBM50335554
(({[({[2-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)e...)Show SMILES Nc1nc2n(CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C8H14N5O11P3/c9-8-11-6-5(7(14)12-8)10-3-13(6)1-2-22-4-25(15,16)23-27(20,21)24-26(17,18)19/h3H,1-2,4H2,(H,15,16)(H,20,21)(H2,17,18,19)(H3,9,11,12,14) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
USA.
Curated by ChEMBL
| Assay Description Inhibition of human DNA polymerase alpha by microplate reader analysis |
Antimicrob Agents Chemother 53: 2777-84 (2009)
Article DOI: 10.1128/AAC.00103-09 BindingDB Entry DOI: 10.7270/Q2M32W2N |
More data for this Ligand-Target Pair | |
DNA polymerase subunit gamma-1
(Homo sapiens (Human)) | BDBM50335554
(({[({[2-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)e...)Show SMILES Nc1nc2n(CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C8H14N5O11P3/c9-8-11-6-5(7(14)12-8)10-3-13(6)1-2-22-4-25(15,16)23-27(20,21)24-26(17,18)19/h3H,1-2,4H2,(H,15,16)(H,20,21)(H2,17,18,19)(H3,9,11,12,14) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
USA.
Curated by ChEMBL
| Assay Description Inhibition of human DNA polymerase gamma by microplate reader analysis |
Antimicrob Agents Chemother 53: 2777-84 (2009)
Article DOI: 10.1128/AAC.00103-09 BindingDB Entry DOI: 10.7270/Q2M32W2N |
More data for this Ligand-Target Pair | |
DNA polymerase beta
(Homo sapiens (Human)) | BDBM50335554
(({[({[2-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)e...)Show SMILES Nc1nc2n(CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C8H14N5O11P3/c9-8-11-6-5(7(14)12-8)10-3-13(6)1-2-22-4-25(15,16)23-27(20,21)24-26(17,18)19/h3H,1-2,4H2,(H,15,16)(H,20,21)(H2,17,18,19)(H3,9,11,12,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
USA.
Curated by ChEMBL
| Assay Description Inhibition of human DNA polymerase beta by microplate reader analysis |
Antimicrob Agents Chemother 53: 2777-84 (2009)
Article DOI: 10.1128/AAC.00103-09 BindingDB Entry DOI: 10.7270/Q2M32W2N |
More data for this Ligand-Target Pair | |