BDBM50335615 6-bromo-2-(4-methoxyphenyl)-7-(4-(pyridin-4-ylmethyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridine::CHEMBL1651451

SMILES: COc1ccc(cc1)-c1nc2ncc(Br)c(N3CCN(Cc4ccncc4)CC3)c2[nH]1

InChI Key: InChIKey=UYBVTIPOQNWOBR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50335615 (6-bromo-2-(4-methoxyphenyl)-7-(4-(pyridin-4-ylmeth...) Show SMILES COc1ccc(cc1)-c1nc2ncc(Br)c(N3CCN(Cc4ccncc4)CC3)c2[nH]1 Show InChI InChI=1S/C23H23BrN6O/c1-31-18-4-2-17(3-5-18)22-27-20-21(19(24)14-26-23(20)28-22)30-12-10-29(11-13-30)15-16-6-8-25-9-7-16/h2-9,14H,10-13,15H2,1H3,(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of Aurora A				Eur J Med Chem 46: 77-94 (2010) Article DOI: 10.1016/j.ejmech.2010.10.017 BindingDB Entry DOI: 10.7270/Q25X296N
					More data for this Ligand-Target Pair