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BDBM50335616 4-((4-(6-bromo-2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)methyl)-2-isopropyloxazole::CHEMBL1651452

SMILES: COc1ccc(cc1)-c1nc2ncc(Br)c(N3CCN(Cc4coc(n4)C(C)C)CC3)c2[nH]1

InChI Key: InChIKey=SCAMHRDMXZULEX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335616   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))
BDBM50335616
PNG
(4-((4-(6-bromo-2-(4-methoxyphenyl)-3H-imidazo[4,5-...)
Show SMILES COc1ccc(cc1)-c1nc2ncc(Br)c(N3CCN(Cc4coc(n4)C(C)C)CC3)c2[nH]1
Show InChI InChI=1S/C24H27BrN6O2/c1-15(2)24-27-17(14-33-24)13-30-8-10-31(11-9-30)21-19(25)12-26-23-20(21)28-22(29-23)16-4-6-18(32-3)7-5-16/h4-7,12,14-15H,8-11,13H2,1-3H3,(H,26,28,29)
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Article
PubMed
n/an/a 81n/an/an/an/an/an/a



Jinan University

Curated by ChEMBL


Assay Description
Inhibition of Aurora A


Eur J Med Chem 46: 77-94 (2010)


Article DOI: 10.1016/j.ejmech.2010.10.017
BindingDB Entry DOI: 10.7270/Q25X296N
More data for this
Ligand-Target Pair