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BDBM50336361 4-Hydroxybenzyl 2,4-dihydroxybenzoate::CHEMBL1668051

SMILES: Oc1ccc(COC(=O)c2ccc(O)cc2O)cc1

InChI Key: InChIKey=JJJRYFPXKQHIAS-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336361   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosinase


(Agaricus bisporus (Common mushroom))
BDBM50336361
PNG
(4-Hydroxybenzyl 2,4-dihydroxybenzoate | CHEMBL1668...)
Show SMILES Oc1ccc(COC(=O)c2ccc(O)cc2O)cc1
Show InChI InChI=1S/C14H12O5/c15-10-3-1-9(2-4-10)8-19-14(18)12-6-5-11(16)7-13(12)17/h1-7,15-17H,8H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.11E+3n/an/an/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Competitive inhibition of mushroom tyrosinase by Lineweaver-Burk plot analysis


Bioorg Med Chem 19: 1167-71 (2011)


Article DOI: 10.1016/j.bmc.2010.12.051
BindingDB Entry DOI: 10.7270/Q2RJ4JRZ
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (Common mushroom))
BDBM50336361
PNG
(4-Hydroxybenzyl 2,4-dihydroxybenzoate | CHEMBL1668...)
Show SMILES Oc1ccc(COC(=O)c2ccc(O)cc2O)cc1
Show InChI InChI=1S/C14H12O5/c15-10-3-1-9(2-4-10)8-19-14(18)12-6-5-11(16)7-13(12)17/h1-7,15-17H,8H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.69E+3n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase preincubated for 20 mins


Bioorg Med Chem 19: 1167-71 (2011)


Article DOI: 10.1016/j.bmc.2010.12.051
BindingDB Entry DOI: 10.7270/Q2RJ4JRZ
More data for this
Ligand-Target Pair