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BDBM50336474 CHEMBL1668495::ethyl 4-(3,4-dimethoxyphenyl)-2-(3-(4-methylpiperidin-1-yl)propanamido)thiophene-3-carboxylate

SMILES: CCOC(=O)c1c(NC(=O)CCN2CCC(C)CC2)scc1-c1ccc(OC)c(OC)c1

InChI Key: InChIKey=OKIRYLJKQDJPIL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336474   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acetylcholinesterase


(Electrophorus electricus (Electric eel))		BDBM50336474
PNG
(CHEMBL1668495 | ethyl 4-(3,4-dimethoxyphenyl)-2-(3...)
Show SMILES CCOC(=O)c1c(NC(=O)CCN2CCC(C)CC2)scc1-c1ccc(OC)c(OC)c1
Show InChI InChI=1S/C24H32N2O5S/c1-5-31-24(28)22-18(17-6-7-19(29-3)20(14-17)30-4)15-32-23(22)25-21(27)10-13-26-11-8-16(2)9-12-26/h6-7,14-16H,5,8-13H2,1-4H3,(H,25,27)
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PC sid
UniChem

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Article
PubMed
n/an/a 3.28E+3n/an/an/an/an/an/a



National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL


Assay Description
Inhibition of electric eel AChE by Ellman's method

Bioorg Med Chem Lett 21: 1105-12 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.131
BindingDB Entry DOI: 10.7270/Q2V988B9
More data for this
Ligand-Target Pair