BDBM50336721 4-(3,3-Dimethyl-butyrylamino)-N-(4,5-dimethyl-thiazol-2-yl)-benzamide::CHEMBL1671925

SMILES: Cc1nc(NC(=O)c2ccc(NC(=O)CC(C)(C)C)cc2)sc1C

InChI Key: InChIKey=YETLEIOGLMOZOZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336721   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50336721 (4-(3,3-Dimethyl-butyrylamino)-N-(4,5-dimethyl-thia...) Show SMILES Cc1nc(NC(=O)c2ccc(NC(=O)CC(C)(C)C)cc2)sc1C Show InChI InChI=1S/C18H23N3O2S/c1-11-12(2)24-17(19-11)21-16(23)13-6-8-14(9-7-13)20-15(22)10-18(3,4)5/h6-9H,10H2,1-5H3,(H,20,22)(H,19,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation counting				J Med Chem 54: 751-64 (2012) Article DOI: 10.1021/jm1008659 BindingDB Entry DOI: 10.7270/Q23X87N9
					More data for this Ligand-Target Pair