null
SMILES: Cc1ccc(cc1NC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(=O)Nc2cc(ccc2C)C(=O)Nc2ccc(c3cc(cc(c23)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O)c1)C(=O)Nc1ccc(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O
InChI Key: InChIKey=FIAFUQMPZJWCLV-UHFFFAOYSA-N
PDB links: 14 PDB IDs match this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50336799 (5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
MediChem Research, Inc. Curated by ChEMBL | Assay Description Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coli | J Nat Prod 60: 884-8 (1997) Article DOI: 10.1021/np9700275 BindingDB Entry DOI: 10.7270/Q2JD50MP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA primase (Bacillus anthracis (Firmicutes)) | BDBM50336799 (5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | 8.8 | n/a |
University of Michigan | Assay Description The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP... | Biochemistry 52: 6905-10 (2013) Article DOI: 10.1021/bi4011286 BindingDB Entry DOI: 10.7270/Q2ZC81JQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human)) | BDBM50336799 (5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 2.62E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ikerchem, S.L.; Universidad del Pais Vasco US Patent | Assay Description 50 uM of substrate peptide (acetylated AMC-labeled peptide from p53 residues 379-382, RHKKAc, BioMol. Cat. #KI-177), 91 nM of human SIRT1 (full lengt... | US Patent US8835659 (2014) BindingDB Entry DOI: 10.7270/Q29K48ZN | |||||||||||
More data for this Ligand-Target Pair |
<< First | Previous | Displayed 51 to 53 (of 53 total ) |