BDBM50336827 3-[(2-Aminothiazol)-4-ethynyl]-5-fluorobenzonitrile::CHEMBL1672272

SMILES: Nc1nc(cs1)C#Cc1cc(F)cc(c1)C#N

InChI Key: InChIKey=XVBCHFJLODWFML-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336827   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50336827 (3-[(2-Aminothiazol)-4-ethynyl]-5-fluorobenzonitril...) Show SMILES Nc1nc(cs1)C#Cc1cc(F)cc(c1)C#N Show InChI InChI=1S/C12H6FN3S/c13-10-4-8(3-9(5-10)6-14)1-2-11-7-17-12(15)16-11/h3-5,7H,(H2,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in rat brain				J Med Chem 54: 901-8 (2012) Article DOI: 10.1021/jm101430m BindingDB Entry DOI: 10.7270/Q26Q1Z7T
					More data for this Ligand-Target Pair