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BDBM50336827 3-[(2-Aminothiazol)-4-ethynyl]-5-fluorobenzonitrile::CHEMBL1672272

SMILES: Nc1nc(cs1)C#Cc1cc(F)cc(c1)C#N

InChI Key: InChIKey=XVBCHFJLODWFML-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336827   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor


(Rattus norvegicus (Rat))
BDBM50336827
PNG
(3-[(2-Aminothiazol)-4-ethynyl]-5-fluorobenzonitril...)
Show SMILES Nc1nc(cs1)C#Cc1cc(F)cc(c1)C#N
Show InChI InChI=1S/C12H6FN3S/c13-10-4-8(3-9(5-10)6-14)1-2-11-7-17-12(15)16-11/h3-5,7H,(H2,15,16)
PDB
MMDB

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Similars

Article
PubMed
0.25n/an/an/an/an/an/an/an/a



National Institute of Mental Health

Curated by ChEMBL


Assay Description
Displacement of [3H]MPEP from mGluR5 in rat brain


J Med Chem 54: 901-8 (2012)

More data for this
Ligand-Target Pair