BDBM50336832 2-(3-((2-Chlorothiazol)-4-yl)ethynyl)-phenyl)acetonitrile::CHEMBL1672277

SMILES: Clc1nc(cs1)C#Cc1cccc(CC#N)c1

InChI Key: InChIKey=IGXZWWWSIANJPG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336832   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50336832 (2-(3-((2-Chlorothiazol)-4-yl)ethynyl)-phenyl)aceto...) Show SMILES Clc1nc(cs1)C#Cc1cccc(CC#N)c1 Show InChI InChI=1S/C13H7ClN2S/c14-13-16-12(9-17-13)5-4-10-2-1-3-11(8-10)6-7-15/h1-3,8-9H,6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in rat brain				J Med Chem 54: 901-8 (2012) Article DOI: 10.1021/jm101430m BindingDB Entry DOI: 10.7270/Q26Q1Z7T
					More data for this Ligand-Target Pair