BDBM50337364 3-methoxy-4-hydroxybenzoic acid::4-Hydroxy-3-methoxy-benzoic acid::4-hydroxy-3-methoxybenzoic acid::4-hydroxyl-3-methoxybenzoic acid::CHEMBL120568::Vanilic acid::Vanillic acid (M2)

SMILES: COc1cc(ccc1O)C(O)=O

InChI Key: InChIKey=WKOLLVMJNQIZCI-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50337364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Xanthine dehydrogenase (Bos taurus (Bovine))	BDBM50337364 (3-methoxy-4-hydroxybenzoic acid | 4-Hydroxy-3-meth...) Show SMILES COc1cc(ccc1O)C(O)=O Show InChI InChI=1S/C8H8O4/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,9H,1H3,(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	7.6	25
SRTM University, Nanded, Maharashtra, 431606, India; Department of Molecular Biotechnology, College of Life and Environmental Sciences, Konkuk University, Seoul, 143-701, South Korea.					Assay Description Inhibition of xanthine oxidase (XO) by each isolated phenolics was measured by following the decrease in the uric acid formation at 293nm at 25°...				Chem Biol Drug Des 83: 119-25 (2014) Article DOI: 10.1111/cbdd.12205 BindingDB Entry DOI: 10.7270/Q2Z89B2H
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Alpha-glucosidase MAL12 (Saccharomyces cerevisiae)	BDBM50337364 (3-methoxy-4-hydroxybenzoic acid | 4-Hydroxy-3-meth...) Show SMILES COc1cc(ccc1O)C(O)=O Show InChI InChI=1S/C8H8O4/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,9H,1H3,(H,10,11)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
SRTM University, Nanded, Maharashtra, 431606, India; Department of Molecular Biotechnology, College of Life and Environmental Sciences, Konkuk University, Seoul, 143-701, South Korea.					Assay Description The assay was performed using isolated phenolics from maize, and inhibition was determined according to previously described method.				Chem Biol Drug Des 83: 119-25 (2014) Article DOI: 10.1111/cbdd.12205 BindingDB Entry DOI: 10.7270/Q2Z89B2H
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Alpha-glucosidase MAL12 (Saccharomyces cerevisiae)	BDBM50337364 (3-methoxy-4-hydroxybenzoic acid | 4-Hydroxy-3-meth...) Show SMILES COc1cc(ccc1O)C(O)=O Show InChI InChI=1S/C8H8O4/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,9H,1H3,(H,10,11)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	7.0	25
Kinki University					Assay Description α-glucosidase (25 μL, 0.2 U/mL), 25 μL of various concentrations of samples, and 175 μL of 50 mM sodium phosphate buffer (pH 7.0)...				J Enzyme Inhib Med Chem 28: 1162-70 (2013) Article DOI: 10.3109/14756366.2012.719503 BindingDB Entry DOI: 10.7270/Q22F7MCR
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Anthrax toxin receptor 2 (Homo sapiens)	BDBM50337364 (3-methoxy-4-hydroxybenzoic acid | 4-Hydroxy-3-meth...) Show SMILES COc1cc(ccc1O)C(O)=O Show InChI InChI=1S/C8H8O4/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,9H,1H3,(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...				J Med Chem 56: 1940-5 (2013) Article DOI: 10.1021/jm301558t BindingDB Entry DOI: 10.7270/Q2BP05Q3
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Enoyl-acyl-carrier protein reductase (Plasmodium falciparum)	BDBM50337364 (3-methoxy-4-hydroxybenzoic acid | 4-Hydroxy-3-meth...) Show SMILES COc1cc(ccc1O)C(O)=O Show InChI InChI=1S/C8H8O4/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,9H,1H3,(H,10,11)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum enoyl-ACP reductase assessed as oxidation of NADH to NAD+ after 10 mins by spectrophotometric analysis				Bioorg Med Chem Lett 22: 610-2 (2011) Article DOI: 10.1016/j.bmcl.2011.10.072 BindingDB Entry DOI: 10.7270/Q2K35V3H
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Thiopurine S-methyltransferase (Homo sapiens (Human))	BDBM50337364 (3-methoxy-4-hydroxybenzoic acid | 4-Hydroxy-3-meth...) Show SMILES COc1cc(ccc1O)C(O)=O Show InChI InChI=1S/C8H8O4/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,9H,1H3,(H,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.79E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of purified human kidney thiopurine methyltransferase (TPMT)				J Med Chem 29: 354-8 (1986) BindingDB Entry DOI: 10.7270/Q2445NPZ
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Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50337364 (3-methoxy-4-hydroxybenzoic acid | 4-Hydroxy-3-meth...) Show SMILES COc1cc(ccc1O)C(O)=O Show InChI InChI=1S/C8H8O4/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,9H,1H3,(H,10,11)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kinki University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using L-tyrosine as substrate preincubated for 10 mins followed by enzyme addition measured after 20 mins by microp...				Bioorg Med Chem Lett 23: 6580-4 (2013) Article DOI: 10.1016/j.bmcl.2013.10.066 BindingDB Entry DOI: 10.7270/Q2QZ2DW5
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Pancreatic lipase (Sus scrofa (Pig))	BDBM50337364 (3-methoxy-4-hydroxybenzoic acid | 4-Hydroxy-3-meth...) Show SMILES COc1cc(ccc1O)C(O)=O Show InChI InChI=1S/C8H8O4/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,9H,1H3,(H,10,11)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Daegu Haany University Curated by ChEMBL					Assay Description Inhibition of pig pancreatic lipase assessed as p-NPB hydrolysis by ELISA				Bioorg Med Chem Lett 21: 1512-4 (2011) Article DOI: 10.1016/j.bmcl.2010.12.122 BindingDB Entry DOI: 10.7270/Q2GQ6Z1H
					More data for this Ligand-Target Pair