BDBM50337408 (1S,2R)-N-benzyl-1-(3,4-dichlorophenyl)-N-methyl-2-((4-(methylsulfonamido)-4-phenylpiperidin-1-yl)methyl)cyclopropanecarboxamide::CHEMBL1682673
SMILES: CN(Cc1ccccc1)C(=O)[C@]1(C[C@H]1CN1CCC(CC1)(NS(C)(=O)=O)c1ccccc1)c1ccc(Cl)c(Cl)c1
InChI Key: InChIKey=BKYRIMQMIWLUBG-SUYBVONHSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuromedin-K receptor (Homo sapiens (Human)) | BDBM50337408 ((1S,2R)-N-benzyl-1-(3,4-dichlorophenyl)-N-methyl-2...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S Curated by ChEMBL | Assay Description Displacement of [3H]Lu AE93103 from human NK3 receptor expressed in BHK cells | Bioorg Med Chem Lett 21: 1498-501 (2011) Article DOI: 10.1016/j.bmcl.2010.12.135 BindingDB Entry DOI: 10.7270/Q23J3D8R | |||||||||||
More data for this Ligand-Target Pair |