BDBM50337433 CHEMBL1681797::rac-2-((4-acetamido-4-phenylpiperidin-1-yl)methyl)-1-(3,4-dichlorophenyl)-N-methyl-N-(4-methylbenzyl)cyclopropanecarboxamide

SMILES: CN(Cc1ccc(C)cc1)C(=O)C1(CC1CN1CCC(CC1)(NC(C)=O)c1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=XQZPJUKBNPBJEI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50337433 (CHEMBL1681797 | rac-2-((4-acetamido-4-phenylpiperi...) Show SMILES CN(Cc1ccc(C)cc1)C(=O)C1(CC1CN1CCC(CC1)(NC(C)=O)c1ccccc1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C33H37Cl2N3O2/c1-23-9-11-25(12-10-23)21-37(3)31(40)33(27-13-14-29(34)30(35)19-27)20-28(33)22-38-17-15-32(16-18-38,36-24(2)39)26-7-5-4-6-8-26/h4-14,19,28H,15-18,20-22H2,1-3H3,(H,36,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]Lu AE93103 from human NK3 receptor expressed in BHK cells				Bioorg Med Chem Lett 21: 1498-501 (2011) Article DOI: 10.1016/j.bmcl.2010.12.135 BindingDB Entry DOI: 10.7270/Q23J3D8R
					More data for this Ligand-Target Pair