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BDBM50337439 CHEMBL1682641::rac-2-((4-acetamido-4-phenylpiperidin-1-yl)methyl)-N-(3,4-dichlorobenzyl)-1-(3,4-dichlorophenyl)-N-methylcyclopropanecarboxamide

SMILES: CN(Cc1ccc(Cl)c(Cl)c1)C(=O)C1(CC1CN1CCC(CC1)(NC(C)=O)c1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=YUJFTKLYMNNTRQ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337439   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuromedin-K receptor


(Homo sapiens (Human))		BDBM50337439
PNG
(CHEMBL1682641 | rac-2-((4-acetamido-4-phenylpiperi...)
Show SMILES CN(Cc1ccc(Cl)c(Cl)c1)C(=O)C1(CC1CN1CCC(CC1)(NC(C)=O)c1ccccc1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C32H33Cl4N3O2/c1-21(40)37-31(23-6-4-3-5-7-23)12-14-39(15-13-31)20-25-18-32(25,24-9-11-27(34)29(36)17-24)30(41)38(2)19-22-8-10-26(33)28(35)16-22/h3-11,16-17,25H,12-15,18-20H2,1-2H3,(H,37,40)
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Article
PubMed
 13n/an/an/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]Lu AE93103 from human NK3 receptor expressed in BHK cells

Bioorg Med Chem Lett 21: 1498-501 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.135
BindingDB Entry DOI: 10.7270/Q23J3D8R
More data for this
Ligand-Target Pair