BDBM50337795 (6aR,10aR)-6,6,9-trimethyl-3-(octan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol::CHEMBL1683645
SMILES: CCCCCCC(C)c1cc(O)c2[C@@H]3CC(C)=CC[C@H]3C(C)(C)Oc2c1
InChI Key: InChIKey=SOOAIMVOTCSILP-IPNZSQQUSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50337795 ((6aR,10aR)-6,6,9-trimethyl-3-(octan-2-yl)-6a,7,10,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 328 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chaminade University of Honolulu Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorption | Bioorg Med Chem Lett 21: 1371-5 (2011) Checked by Author Article DOI: 10.1016/j.bmcl.2011.01.037 BindingDB Entry DOI: 10.7270/Q21J9B1F | |||||||||||
More data for this Ligand-Target Pair |