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SMILES: FC(F)(F)c1cccc2C(CCOc12)NC(=O)Nc1cccc2[nH]ncc12

InChI Key: InChIKey=CRCCQJDITKRXDH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337978   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50337978
PNG
(1-(1H-indazol-4-yl)-3-(8-(trifluoromethyl)chroman-...)
Show SMILES FC(F)(F)c1cccc2C(CCOc12)NC(=O)Nc1cccc2[nH]ncc12
Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)12-4-1-3-10-14(7-8-27-16(10)12)24-17(26)23-13-5-2-6-15-11(13)9-22-25-15/h1-6,9,14H,7-8H2,(H,22,25)(H2,23,24,26)
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n/an/a 5n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 assessed as inhibition of calcium influx

Bioorg Med Chem Lett 21: 1338-41 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.056
BindingDB Entry DOI: 10.7270/Q20K28W6
More data for this
Ligand-Target Pair