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SMILES: FC(F)(F)Oc1cccc2C(CCOc12)NC(=O)Nc1cccc2[nH]ncc12

InChI Key: InChIKey=XKXJVTYDGSUSKI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337979   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50337979
PNG
(1-(1H-indazol-4-yl)-3-(8-(trifluoromethoxy)chroman...)
Show SMILES FC(F)(F)Oc1cccc2C(CCOc12)NC(=O)Nc1cccc2[nH]ncc12
Show InChI InChI=1S/C18H15F3N4O3/c19-18(20,21)28-15-6-1-3-10-13(7-8-27-16(10)15)24-17(26)23-12-4-2-5-14-11(12)9-22-25-14/h1-6,9,13H,7-8H2,(H,22,25)(H2,23,24,26)
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n/an/a 5n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 assessed as inhibition of calcium influx

Bioorg Med Chem Lett 21: 1338-41 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.056
BindingDB Entry DOI: 10.7270/Q20K28W6
More data for this
Ligand-Target Pair