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SMILES: CN1CCC(NC(=O)Nc2cccc3[nH]ncc23)c2cccc(c12)C(C)(C)C

InChI Key: InChIKey=XGZRRBPKFSGZBB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337988   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50337988
PNG
(1-(8-tert-butyl-1-methyl-1,2,3,4-tetrahydroquinoli...)
Show SMILES CN1CCC(NC(=O)Nc2cccc3[nH]ncc23)c2cccc(c12)C(C)(C)C
Show InChI InChI=1S/C22H27N5O/c1-22(2,3)16-8-5-7-14-18(11-12-27(4)20(14)16)25-21(28)24-17-9-6-10-19-15(17)13-23-26-19/h5-10,13,18H,11-12H2,1-4H3,(H,23,26)(H2,24,25,28)
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n/an/a 6n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 assessed as inhibition of calcium influx

Bioorg Med Chem Lett 21: 1338-41 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.056
BindingDB Entry DOI: 10.7270/Q20K28W6
More data for this
Ligand-Target Pair