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SMILES: FC(F)(F)c1ccc2[C@@H](CCOc2c1)NC(=O)Nc1cccc2[nH]ncc12

InChI Key: InChIKey=LNRLQTQYVBBJBO-CQSZACIVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337998   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50337998
PNG
((R)-1-(1H-indazol-4-yl)-3-(7-(trifluoromethyl)chro...)
Show SMILES FC(F)(F)c1ccc2[C@@H](CCOc2c1)NC(=O)Nc1cccc2[nH]ncc12 |r|
Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)10-4-5-11-14(6-7-27-16(11)8-10)24-17(26)23-13-2-1-3-15-12(13)9-22-25-15/h1-5,8-9,14H,6-7H2,(H,22,25)(H2,23,24,26)/t14-/m1/s1
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n/an/a 4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 assessed as inhibition of calcium influx

Bioorg Med Chem Lett 21: 1338-41 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.056
BindingDB Entry DOI: 10.7270/Q20K28W6
More data for this
Ligand-Target Pair