BDBM50338102 2-(2-(1H-pyrazolo[4,3-b]pyridin-3-yl)-1H-indol-6-yl)acetamide::CHEMBL1684664

SMILES: NC(=O)Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12

InChI Key: InChIKey=HZAJNFWQNYSPOI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338102   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50338102 (2-(2-(1H-pyrazolo[4,3-b]pyridin-3-yl)-1H-indol-6-y...) Show SMILES NC(=O)Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C16H13N5O/c17-14(22)7-9-3-4-10-8-13(19-12(10)6-9)16-15-11(20-21-16)2-1-5-18-15/h1-6,8,19H,7H2,(H2,17,22)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 21: 1852-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.035 BindingDB Entry DOI: 10.7270/Q2MC90BW
					More data for this Ligand-Target Pair