BDBM50338219 1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yloxy)-2-chlorophenyl)-3-(2-methoxyphenyl)urea::CHEMBL1681949

SMILES: CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2ccccc2OC)c(Cl)c1

InChI Key: InChIKey=HYWCNZPMWKYWHG-KIBLKLHPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338219 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2ccccc2OC)c(Cl)c1 Show InChI InChI=1S/C20H19ClN6O4/c1-29-17-6-4-3-5-16(17)27-20(28)26-15-8-7-12(9-14(15)21)31-19-13(10-25-30-2)18(22)23-11-24-19/h3-11H,1-2H3,(H2,22,23,24)(H2,26,27,28)/b25-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair