BDBM50338224 1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yloxy)-2-chlorophenyl)-3-(2,4-difluorobenzyl)urea::CHEMBL1681954

SMILES: CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)NCc2ccc(F)cc2F)c(Cl)c1

InChI Key: InChIKey=RNCPKNKPKGTQPT-HIUVJMHLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338224   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338224 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)NCc2ccc(F)cc2F)c(Cl)c1 Show InChI InChI=1S/C20H17ClF2N6O3/c1-31-28-9-14-18(24)26-10-27-19(14)32-13-4-5-17(15(21)7-13)29-20(30)25-8-11-2-3-12(22)6-16(11)23/h2-7,9-10H,8H2,1H3,(H2,24,26,27)(H2,25,29,30)/b28-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair