Found 5 hits for monomerid = 50338266 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50338266
(CHEMBL1682020 | N-(4-chloro-3-(1H-1,2,4-triazol-5-...)Show SMILES Clc1csc(NC(=O)Cc2cccc3ncccc23)c1-c1nnc[nH]1 Show InChI InChI=1S/C17H12ClN5OS/c18-12-8-25-17(15(12)16-20-9-21-23-16)22-14(24)7-10-3-1-5-13-11(10)4-2-6-19-13/h1-6,8-9H,7H2,(H,22,24)(H,20,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant JNK3 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 21: 1838-43 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.046
BindingDB Entry DOI: 10.7270/Q2Q52PX0 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 9
(Homo sapiens (Human)) | BDBM50338266
(CHEMBL1682020 | N-(4-chloro-3-(1H-1,2,4-triazol-5-...)Show SMILES Clc1csc(NC(=O)Cc2cccc3ncccc23)c1-c1nnc[nH]1 Show InChI InChI=1S/C17H12ClN5OS/c18-12-8-25-17(15(12)16-20-9-21-23-16)22-14(24)7-10-3-1-5-13-11(10)4-2-6-19-13/h1-6,8-9H,7H2,(H,22,24)(H,20,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant JNK2 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 21: 1838-43 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.046
BindingDB Entry DOI: 10.7270/Q2Q52PX0 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50338266
(CHEMBL1682020 | N-(4-chloro-3-(1H-1,2,4-triazol-5-...)Show SMILES Clc1csc(NC(=O)Cc2cccc3ncccc23)c1-c1nnc[nH]1 Show InChI InChI=1S/C17H12ClN5OS/c18-12-8-25-17(15(12)16-20-9-21-23-16)22-14(24)7-10-3-1-5-13-11(10)4-2-6-19-13/h1-6,8-9H,7H2,(H,22,24)(H,20,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant ERK2 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 21: 1838-43 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.046
BindingDB Entry DOI: 10.7270/Q2Q52PX0 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50338266
(CHEMBL1682020 | N-(4-chloro-3-(1H-1,2,4-triazol-5-...)Show SMILES Clc1csc(NC(=O)Cc2cccc3ncccc23)c1-c1nnc[nH]1 Show InChI InChI=1S/C17H12ClN5OS/c18-12-8-25-17(15(12)16-20-9-21-23-16)22-14(24)7-10-3-1-5-13-11(10)4-2-6-19-13/h1-6,8-9H,7H2,(H,22,24)(H,20,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant p38alpha after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 21: 1838-43 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.046
BindingDB Entry DOI: 10.7270/Q2Q52PX0 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM50338266
(CHEMBL1682020 | N-(4-chloro-3-(1H-1,2,4-triazol-5-...)Show SMILES Clc1csc(NC(=O)Cc2cccc3ncccc23)c1-c1nnc[nH]1 Show InChI InChI=1S/C17H12ClN5OS/c18-12-8-25-17(15(12)16-20-9-21-23-16)22-14(24)7-10-3-1-5-13-11(10)4-2-6-19-13/h1-6,8-9H,7H2,(H,22,24)(H,20,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant JNK1 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 21: 1838-43 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.046
BindingDB Entry DOI: 10.7270/Q2Q52PX0 |
More data for this
Ligand-Target Pair | |
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