null

SMILES: CCOC(=O)c1c(NC(=O)Cc2ccc(OC)cc2)scc1C#N

InChI Key: InChIKey=JTVHPFGRRUKYMR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50338272 (CHEMBL1681996 | ethyl 4-cyano-2-(2-(4-methoxypheny...) Show SMILES CCOC(=O)c1c(NC(=O)Cc2ccc(OC)cc2)scc1C#N Show InChI InChI=1S/C17H16N2O4S/c1-3-23-17(21)15-12(9-18)10-24-16(15)19-14(20)8-11-4-6-13(22-2)7-5-11/h4-7,10H,3,8H2,1-2H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant JNK2 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50338272 (CHEMBL1681996 | ethyl 4-cyano-2-(2-(4-methoxypheny...) Show SMILES CCOC(=O)c1c(NC(=O)Cc2ccc(OC)cc2)scc1C#N Show InChI InChI=1S/C17H16N2O4S/c1-3-23-17(21)15-12(9-18)10-24-16(15)19-14(20)8-11-4-6-13(22-2)7-5-11/h4-7,10H,3,8H2,1-2H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant JNK3 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50338272 (CHEMBL1681996 | ethyl 4-cyano-2-(2-(4-methoxypheny...) Show SMILES CCOC(=O)c1c(NC(=O)Cc2ccc(OC)cc2)scc1C#N Show InChI InChI=1S/C17H16N2O4S/c1-3-23-17(21)15-12(9-18)10-24-16(15)19-14(20)8-11-4-6-13(22-2)7-5-11/h4-7,10H,3,8H2,1-2H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant JNK1 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair