BDBM50338279 CHEMBL1682003::methyl 4-methyl-2-(2-(quinoxalin-5-yl)acetamido)thiophene-3-carboxylate

SMILES: COC(=O)c1c(C)csc1NC(=O)Cc1cccc2nccnc12

InChI Key: InChIKey=PNTONLVXRZCBPB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50338279 (CHEMBL1682003 | methyl 4-methyl-2-(2-(quinoxalin-5...) Show SMILES COC(=O)c1c(C)csc1NC(=O)Cc1cccc2nccnc12 Show InChI InChI=1S/C17H15N3O3S/c1-10-9-24-16(14(10)17(22)23-2)20-13(21)8-11-4-3-5-12-15(11)19-7-6-18-12/h3-7,9H,8H2,1-2H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	765	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant JNK2 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50338279 (CHEMBL1682003 | methyl 4-methyl-2-(2-(quinoxalin-5...) Show SMILES COC(=O)c1c(C)csc1NC(=O)Cc1cccc2nccnc12 Show InChI InChI=1S/C17H15N3O3S/c1-10-9-24-16(14(10)17(22)23-2)20-13(21)8-11-4-3-5-12-15(11)19-7-6-18-12/h3-7,9H,8H2,1-2H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant JNK3 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50338279 (CHEMBL1682003 | methyl 4-methyl-2-(2-(quinoxalin-5...) Show SMILES COC(=O)c1c(C)csc1NC(=O)Cc1cccc2nccnc12 Show InChI InChI=1S/C17H15N3O3S/c1-10-9-24-16(14(10)17(22)23-2)20-13(21)8-11-4-3-5-12-15(11)19-7-6-18-12/h3-7,9H,8H2,1-2H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant JNK1 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair