null

SMILES: COC(=O)c1c(C)csc1NC(=O)Cc1cccc2cnccc12

InChI Key: InChIKey=YAOWLMDOOICXCZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50338281 (CHEMBL1681791 | methyl 2-(2-(isoquinolin-5-yl)acet...) Show SMILES COC(=O)c1c(C)csc1NC(=O)Cc1cccc2cnccc12 Show InChI InChI=1S/C18H16N2O3S/c1-11-10-24-17(16(11)18(22)23-2)20-15(21)8-12-4-3-5-13-9-19-7-6-14(12)13/h3-7,9-10H,8H2,1-2H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	863	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant JNK2 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50338281 (CHEMBL1681791 | methyl 2-(2-(isoquinolin-5-yl)acet...) Show SMILES COC(=O)c1c(C)csc1NC(=O)Cc1cccc2cnccc12 Show InChI InChI=1S/C18H16N2O3S/c1-11-10-24-17(16(11)18(22)23-2)20-15(21)8-12-4-3-5-13-9-19-7-6-14(12)13/h3-7,9-10H,8H2,1-2H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant JNK3 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50338281 (CHEMBL1681791 | methyl 2-(2-(isoquinolin-5-yl)acet...) Show SMILES COC(=O)c1c(C)csc1NC(=O)Cc1cccc2cnccc12 Show InChI InChI=1S/C18H16N2O3S/c1-11-10-24-17(16(11)18(22)23-2)20-15(21)8-12-4-3-5-13-9-19-7-6-14(12)13/h3-7,9-10H,8H2,1-2H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant JNK1 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair