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SMILES: COc1ccc(CC(=O)Nc2scc(C)c2-c2nnc(C)[nH]2)cc1

InChI Key: InChIKey=LXZLCVFQXWMBJR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338283   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 9


(Homo sapiens (Human))
BDBM50338283
PNG
(2-(4-methoxyphenyl)-N-(4-methyl-3-(3-methyl-1H-1,2...)
Show SMILES COc1ccc(CC(=O)Nc2scc(C)c2-c2nnc(C)[nH]2)cc1
Show InChI InChI=1S/C17H18N4O2S/c1-10-9-24-17(15(10)16-18-11(2)20-21-16)19-14(22)8-12-4-6-13(23-3)7-5-12/h4-7,9H,8H2,1-3H3,(H,19,22)(H,18,20,21)
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Article
PubMed
n/an/a 824n/an/an/an/an/an/a



Elan Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant JNK2 after 60 mins by TR-FRET assay


Bioorg Med Chem Lett 21: 1838-43 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.046
BindingDB Entry DOI: 10.7270/Q2Q52PX0
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 10


(Homo sapiens (Human))
BDBM50338283
PNG
(2-(4-methoxyphenyl)-N-(4-methyl-3-(3-methyl-1H-1,2...)
Show SMILES COc1ccc(CC(=O)Nc2scc(C)c2-c2nnc(C)[nH]2)cc1
Show InChI InChI=1S/C17H18N4O2S/c1-10-9-24-17(15(10)16-18-11(2)20-21-16)19-14(22)8-12-4-6-13(23-3)7-5-12/h4-7,9H,8H2,1-3H3,(H,19,22)(H,18,20,21)
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UniChem

Patents


Similars

Article
PubMed
n/an/a 465n/an/an/an/an/an/a



Elan Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant JNK3 after 60 mins by TR-FRET assay


Bioorg Med Chem Lett 21: 1838-43 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.046
BindingDB Entry DOI: 10.7270/Q2Q52PX0
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 8


(Homo sapiens (Human))
BDBM50338283
PNG
(2-(4-methoxyphenyl)-N-(4-methyl-3-(3-methyl-1H-1,2...)
Show SMILES COc1ccc(CC(=O)Nc2scc(C)c2-c2nnc(C)[nH]2)cc1
Show InChI InChI=1S/C17H18N4O2S/c1-10-9-24-17(15(10)16-18-11(2)20-21-16)19-14(22)8-12-4-6-13(23-3)7-5-12/h4-7,9H,8H2,1-3H3,(H,19,22)(H,18,20,21)
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

B.MOAD
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antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 331n/an/an/an/an/an/a



Elan Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant JNK1 after 60 mins by TR-FRET assay


Bioorg Med Chem Lett 21: 1838-43 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.046
BindingDB Entry DOI: 10.7270/Q2Q52PX0
More data for this
Ligand-Target Pair