BDBM50338286 CHEMBL1682009::N-(4-methyl-3-(3-methyl-1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(quinoxalin-5-yl)acetamide

SMILES: Cc1nnc([nH]1)-c1c(C)csc1NC(=O)Cc1cccc2nccnc12

InChI Key: InChIKey=UBQAXNUSTYBVJI-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50338286 (CHEMBL1682009 | N-(4-methyl-3-(3-methyl-1H-1,2,4-t...) Show SMILES Cc1nnc([nH]1)-c1c(C)csc1NC(=O)Cc1cccc2nccnc12 Show InChI InChI=1S/C18H16N6OS/c1-10-9-26-18(15(10)17-21-11(2)23-24-17)22-14(25)8-12-4-3-5-13-16(12)20-7-6-19-13/h3-7,9H,8H2,1-2H3,(H,22,25)(H,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant JNK2 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50338286 (CHEMBL1682009 | N-(4-methyl-3-(3-methyl-1H-1,2,4-t...) Show SMILES Cc1nnc([nH]1)-c1c(C)csc1NC(=O)Cc1cccc2nccnc12 Show InChI InChI=1S/C18H16N6OS/c1-10-9-26-18(15(10)17-21-11(2)23-24-17)22-14(25)8-12-4-3-5-13-16(12)20-7-6-19-13/h3-7,9H,8H2,1-2H3,(H,22,25)(H,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	298	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant JNK1 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50338286 (CHEMBL1682009 | N-(4-methyl-3-(3-methyl-1H-1,2,4-t...) Show SMILES Cc1nnc([nH]1)-c1c(C)csc1NC(=O)Cc1cccc2nccnc12 Show InChI InChI=1S/C18H16N6OS/c1-10-9-26-18(15(10)17-21-11(2)23-24-17)22-14(25)8-12-4-3-5-13-16(12)20-7-6-19-13/h3-7,9H,8H2,1-2H3,(H,22,25)(H,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	594	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant JNK3 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50338286 (CHEMBL1682009 | N-(4-methyl-3-(3-methyl-1H-1,2,4-t...) Show SMILES Cc1nnc([nH]1)-c1c(C)csc1NC(=O)Cc1cccc2nccnc12 Show InChI InChI=1S/C18H16N6OS/c1-10-9-26-18(15(10)17-21-11(2)23-24-17)22-14(25)8-12-4-3-5-13-16(12)20-7-6-19-13/h3-7,9H,8H2,1-2H3,(H,22,25)(H,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant ERK2 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50338286 (CHEMBL1682009 | N-(4-methyl-3-(3-methyl-1H-1,2,4-t...) Show SMILES Cc1nnc([nH]1)-c1c(C)csc1NC(=O)Cc1cccc2nccnc12 Show InChI InChI=1S/C18H16N6OS/c1-10-9-26-18(15(10)17-21-11(2)23-24-17)22-14(25)8-12-4-3-5-13-16(12)20-7-6-19-13/h3-7,9H,8H2,1-2H3,(H,22,25)(H,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant p38alpha after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 21: 1838-43 (2011) Article DOI: 10.1016/j.bmcl.2011.01.046 BindingDB Entry DOI: 10.7270/Q2Q52PX0
					More data for this Ligand-Target Pair