Found 5 hits for monomerid = 50338424 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Fibroblast activation protein alpha
(Homo sapiens (Human)) | BDBM50338424
((R)-2-(2,5-difluorophenyl)-1-(1-(methylsulfonyl)pi...)Show SMILES CS(=O)(=O)N1CCC(CC1)[C@H](N)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C14H20F2N2O2S/c1-21(19,20)18-6-4-10(5-7-18)14(17)9-11-8-12(15)2-3-13(11)16/h2-3,8,10,14H,4-7,9,17H2,1H3/t14-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of FAP |
Bioorg Med Chem Lett 21: 1880-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.060 BindingDB Entry DOI: 10.7270/Q2SX6DJG |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 2 (DPP II)
(Homo sapiens (Human)) | BDBM50338424
((R)-2-(2,5-difluorophenyl)-1-(1-(methylsulfonyl)pi...)Show SMILES CS(=O)(=O)N1CCC(CC1)[C@H](N)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C14H20F2N2O2S/c1-21(19,20)18-6-4-10(5-7-18)14(17)9-11-8-12(15)2-3-13(11)16/h2-3,8,10,14H,4-7,9,17H2,1H3/t14-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of QPP |
Bioorg Med Chem Lett 21: 1880-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.060 BindingDB Entry DOI: 10.7270/Q2SX6DJG |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50338424
((R)-2-(2,5-difluorophenyl)-1-(1-(methylsulfonyl)pi...)Show SMILES CS(=O)(=O)N1CCC(CC1)[C@H](N)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C14H20F2N2O2S/c1-21(19,20)18-6-4-10(5-7-18)14(17)9-11-8-12(15)2-3-13(11)16/h2-3,8,10,14H,4-7,9,17H2,1H3/t14-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 21: 1880-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.060 BindingDB Entry DOI: 10.7270/Q2SX6DJG |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase VIII
(Homo sapiens (Human)) | BDBM50338424
((R)-2-(2,5-difluorophenyl)-1-(1-(methylsulfonyl)pi...)Show SMILES CS(=O)(=O)N1CCC(CC1)[C@H](N)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C14H20F2N2O2S/c1-21(19,20)18-6-4-10(5-7-18)14(17)9-11-8-12(15)2-3-13(11)16/h2-3,8,10,14H,4-7,9,17H2,1H3/t14-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP8 |
Bioorg Med Chem Lett 21: 1880-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.060 BindingDB Entry DOI: 10.7270/Q2SX6DJG |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50338424
((R)-2-(2,5-difluorophenyl)-1-(1-(methylsulfonyl)pi...)Show SMILES CS(=O)(=O)N1CCC(CC1)[C@H](N)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C14H20F2N2O2S/c1-21(19,20)18-6-4-10(5-7-18)14(17)9-11-8-12(15)2-3-13(11)16/h2-3,8,10,14H,4-7,9,17H2,1H3/t14-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP9 |
Bioorg Med Chem Lett 21: 1880-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.060 BindingDB Entry DOI: 10.7270/Q2SX6DJG |
More data for this Ligand-Target Pair | |