Found 5 hits for monomerid = 50338428 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Fibroblast activation protein alpha
(Homo sapiens (Human)) | BDBM50338428
((R)-5-(4-(1-amino-2-(2,5-difluorophenyl)ethyl)pipe...)Show SMILES N[C@H](Cc1cc(F)ccc1F)C1CCN(CC1)c1cncc(c1)C#N |r| Show InChI InChI=1S/C19H20F2N4/c20-16-1-2-18(21)15(8-16)9-19(23)14-3-5-25(6-4-14)17-7-13(10-22)11-24-12-17/h1-2,7-8,11-12,14,19H,3-6,9,23H2/t19-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of FAP |
Bioorg Med Chem Lett 21: 1880-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.060 BindingDB Entry DOI: 10.7270/Q2SX6DJG |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 2 (DPP II)
(Homo sapiens (Human)) | BDBM50338428
((R)-5-(4-(1-amino-2-(2,5-difluorophenyl)ethyl)pipe...)Show SMILES N[C@H](Cc1cc(F)ccc1F)C1CCN(CC1)c1cncc(c1)C#N |r| Show InChI InChI=1S/C19H20F2N4/c20-16-1-2-18(21)15(8-16)9-19(23)14-3-5-25(6-4-14)17-7-13(10-22)11-24-12-17/h1-2,7-8,11-12,14,19H,3-6,9,23H2/t19-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of QPP |
Bioorg Med Chem Lett 21: 1880-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.060 BindingDB Entry DOI: 10.7270/Q2SX6DJG |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase VIII
(Homo sapiens (Human)) | BDBM50338428
((R)-5-(4-(1-amino-2-(2,5-difluorophenyl)ethyl)pipe...)Show SMILES N[C@H](Cc1cc(F)ccc1F)C1CCN(CC1)c1cncc(c1)C#N |r| Show InChI InChI=1S/C19H20F2N4/c20-16-1-2-18(21)15(8-16)9-19(23)14-3-5-25(6-4-14)17-7-13(10-22)11-24-12-17/h1-2,7-8,11-12,14,19H,3-6,9,23H2/t19-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP8 |
Bioorg Med Chem Lett 21: 1880-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.060 BindingDB Entry DOI: 10.7270/Q2SX6DJG |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50338428
((R)-5-(4-(1-amino-2-(2,5-difluorophenyl)ethyl)pipe...)Show SMILES N[C@H](Cc1cc(F)ccc1F)C1CCN(CC1)c1cncc(c1)C#N |r| Show InChI InChI=1S/C19H20F2N4/c20-16-1-2-18(21)15(8-16)9-19(23)14-3-5-25(6-4-14)17-7-13(10-22)11-24-12-17/h1-2,7-8,11-12,14,19H,3-6,9,23H2/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP4 |
Bioorg Med Chem Lett 21: 1880-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.060 BindingDB Entry DOI: 10.7270/Q2SX6DJG |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50338428
((R)-5-(4-(1-amino-2-(2,5-difluorophenyl)ethyl)pipe...)Show SMILES N[C@H](Cc1cc(F)ccc1F)C1CCN(CC1)c1cncc(c1)C#N |r| Show InChI InChI=1S/C19H20F2N4/c20-16-1-2-18(21)15(8-16)9-19(23)14-3-5-25(6-4-14)17-7-13(10-22)11-24-12-17/h1-2,7-8,11-12,14,19H,3-6,9,23H2/t19-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP9 |
Bioorg Med Chem Lett 21: 1880-6 (2011)
Article DOI: 10.1016/j.bmcl.2010.12.060 BindingDB Entry DOI: 10.7270/Q2SX6DJG |
More data for this Ligand-Target Pair | |