BDBM50338511 (3'S,4'S)-4'-amino-1'-(6-(cyclopropylamino)pyrimidin-4-yl)-1,3'-bipyrrolidin-2-one::CHEMBL1683564

SMILES: N[C@H]1CN(C[C@@H]1N1CCCC1=O)c1cc(NC2CC2)ncn1

InChI Key: InChIKey=LHPVKAQXRWDGKP-RYUDHWBXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338511   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50338511 ((3'S,4'S)-4'-amino-1'-(6-(cyclopropylamino)pyrimid...) Show SMILES N[C@H]1CN(C[C@@H]1N1CCCC1=O)c1cc(NC2CC2)ncn1 |r| Show InChI InChI=1S/C15H22N6O/c16-11-7-20(8-12(11)21-5-1-2-15(21)22)14-6-13(17-9-18-14)19-10-3-4-10/h6,9-12H,1-5,7-8,16H2,(H,17,18,19)/t11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem Lett 21: 1810-4 (2011) Article DOI: 10.1016/j.bmcl.2011.01.055 BindingDB Entry DOI: 10.7270/Q28W3DM7
					More data for this Ligand-Target Pair