BDBM50338515 1-((3S,4S)-4-amino-1-(6-(3,3-difluoropyrrolidin-1-yl)pyrimidin-4-yl)pyrrolidin-3-yl)piperidin-2-one::CHEMBL1683568

SMILES: N[C@H]1CN(C[C@@H]1N1CCCCC1=O)c1cc(ncn1)N1CCC(F)(F)C1

InChI Key: InChIKey=BCHZEUXVXZHVAQ-STQMWFEESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50338515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50338515 (1-((3S,4S)-4-amino-1-(6-(3,3-difluoropyrrolidin-1-...) Show SMILES N[C@H]1CN(C[C@@H]1N1CCCCC1=O)c1cc(ncn1)N1CCC(F)(F)C1 |r| Show InChI InChI=1S/C17H24F2N6O/c18-17(19)4-6-23(10-17)14-7-15(22-11-21-14)24-8-12(20)13(9-24)25-5-2-1-3-16(25)26/h7,11-13H,1-6,8-10,20H2/t12-,13-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of DPP8				Bioorg Med Chem Lett 21: 1810-4 (2011) Article DOI: 10.1016/j.bmcl.2011.01.055 BindingDB Entry DOI: 10.7270/Q28W3DM7
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50338515 (1-((3S,4S)-4-amino-1-(6-(3,3-difluoropyrrolidin-1-...) Show SMILES N[C@H]1CN(C[C@@H]1N1CCCCC1=O)c1cc(ncn1)N1CCC(F)(F)C1 |r| Show InChI InChI=1S/C17H24F2N6O/c18-17(19)4-6-23(10-17)14-7-15(22-11-21-14)24-8-12(20)13(9-24)25-5-2-1-3-16(25)26/h7,11-13H,1-6,8-10,20H2/t12-,13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem Lett 21: 1810-4 (2011) Article DOI: 10.1016/j.bmcl.2011.01.055 BindingDB Entry DOI: 10.7270/Q28W3DM7
					More data for this Ligand-Target Pair