BDBM50338642 (+)-R-11-(3-(4-((4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine::CHEMBL1684133

SMILES: CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(OCCCn2cc(CCN4CCN(CC4)c4ccccc4OC)nn2)c-31

InChI Key: InChIKey=RXIFDJMCJKEING-MGBGTMOVSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50338642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50338642 ((+)-R-11-(3-(4-((4-(2-Methoxyphenyl)piperazin-1-yl...) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(OCCCn2cc(CCN4CCN(CC4)c4ccccc4OC)nn2)c-31 |r| Show InChI InChI=1S/C37H46N6O2/c1-3-17-41-20-15-28-9-6-11-31-36(28)33(41)26-29-10-7-14-35(37(29)31)45-25-8-18-43-27-30(38-39-43)16-19-40-21-23-42(24-22-40)32-12-4-5-13-34(32)44-2/h4-7,9-14,27,33H,3,8,15-26H2,1-2H3/t33-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D3 receptor expressed in human HEK293 cells by liquid scintillation counter				Bioorg Med Chem 19: 1999-2008 (2011) Article DOI: 10.1016/j.bmc.2011.01.053 BindingDB Entry DOI: 10.7270/Q2HD7VXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50338642 ((+)-R-11-(3-(4-((4-(2-Methoxyphenyl)piperazin-1-yl...) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(OCCCn2cc(CCN4CCN(CC4)c4ccccc4OC)nn2)c-31 |r| Show InChI InChI=1S/C37H46N6O2/c1-3-17-41-20-15-28-9-6-11-31-36(28)33(41)26-29-10-7-14-35(37(29)31)45-25-8-18-43-27-30(38-39-43)16-19-40-21-23-42(24-22-40)32-12-4-5-13-34(32)44-2/h4-7,9-14,27,33H,3,8,15-26H2,1-2H3/t33-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5-HT1A receptor expressed in CHO cells by liquid scintillation counter				Bioorg Med Chem 19: 1999-2008 (2011) Article DOI: 10.1016/j.bmc.2011.01.053 BindingDB Entry DOI: 10.7270/Q2HD7VXH
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50338642 ((+)-R-11-(3-(4-((4-(2-Methoxyphenyl)piperazin-1-yl...) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(OCCCn2cc(CCN4CCN(CC4)c4ccccc4OC)nn2)c-31 |r| Show InChI InChI=1S/C37H46N6O2/c1-3-17-41-20-15-28-9-6-11-31-36(28)33(41)26-29-10-7-14-35(37(29)31)45-25-8-18-43-27-30(38-39-43)16-19-40-21-23-42(24-22-40)32-12-4-5-13-34(32)44-2/h4-7,9-14,27,33H,3,8,15-26H2,1-2H3/t33-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D3 receptor expressed in human HEK293 cells by liquid scintillation counter				Bioorg Med Chem 19: 1999-2008 (2011) Article DOI: 10.1016/j.bmc.2011.01.053 BindingDB Entry DOI: 10.7270/Q2HD7VXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50338642 ((+)-R-11-(3-(4-((4-(2-Methoxyphenyl)piperazin-1-yl...) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(OCCCn2cc(CCN4CCN(CC4)c4ccccc4OC)nn2)c-31 |r| Show InChI InChI=1S/C37H46N6O2/c1-3-17-41-20-15-28-9-6-11-31-36(28)33(41)26-29-10-7-14-35(37(29)31)45-25-8-18-43-27-30(38-39-43)16-19-40-21-23-42(24-22-40)32-12-4-5-13-34(32)44-2/h4-7,9-14,27,33H,3,8,15-26H2,1-2H3/t33-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]Ketanserin from 5-HT2A receptor expressed in CHO cells by liquid scintillation counter				Bioorg Med Chem 19: 1999-2008 (2011) Article DOI: 10.1016/j.bmc.2011.01.053 BindingDB Entry DOI: 10.7270/Q2HD7VXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50338642 ((+)-R-11-(3-(4-((4-(2-Methoxyphenyl)piperazin-1-yl...) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(OCCCn2cc(CCN4CCN(CC4)c4ccccc4OC)nn2)c-31 |r| Show InChI InChI=1S/C37H46N6O2/c1-3-17-41-20-15-28-9-6-11-31-36(28)33(41)26-29-10-7-14-35(37(29)31)45-25-8-18-43-27-30(38-39-43)16-19-40-21-23-42(24-22-40)32-12-4-5-13-34(32)44-2/h4-7,9-14,27,33H,3,8,15-26H2,1-2H3/t33-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor expressed in human HEK293 cells by liquid scintillation counter				Bioorg Med Chem 19: 1999-2008 (2011) Article DOI: 10.1016/j.bmc.2011.01.053 BindingDB Entry DOI: 10.7270/Q2HD7VXH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50338642 ((+)-R-11-(3-(4-((4-(2-Methoxyphenyl)piperazin-1-yl...) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(OCCCn2cc(CCN4CCN(CC4)c4ccccc4OC)nn2)c-31 |r| Show InChI InChI=1S/C37H46N6O2/c1-3-17-41-20-15-28-9-6-11-31-36(28)33(41)26-29-10-7-14-35(37(29)31)45-25-8-18-43-27-30(38-39-43)16-19-40-21-23-42(24-22-40)32-12-4-5-13-34(32)44-2/h4-7,9-14,27,33H,3,8,15-26H2,1-2H3/t33-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor expressed in human HEK293 cells by liquid scintillation counter				Bioorg Med Chem 19: 1999-2008 (2011) Article DOI: 10.1016/j.bmc.2011.01.053 BindingDB Entry DOI: 10.7270/Q2HD7VXH
					More data for this Ligand-Target Pair