BDBM50338683 (R/S)-6-chloro-N-((3S)-1-(2-fluoro-4-(1-methylpyrrolidin-2-yl)phenyl)-2-oxopyrrolidin-3-yl)naphthalene-2-sulfonamide::CHEMBL1684187

SMILES: CN1CCCC1c1ccc(N2CC[C@H](NS(=O)(=O)c3ccc4cc(Cl)ccc4c3)C2=O)c(F)c1

InChI Key: InChIKey=BWMOSLZAUDDHEQ-NQCNTLBGSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50338683 ((R/S)-6-chloro-N-((3S)-1-(2-fluoro-4-(1-methylpyrr...) Show SMILES CN1CCCC1c1ccc(N2CC[C@H](NS(=O)(=O)c3ccc4cc(Cl)ccc4c3)C2=O)c(F)c1 |r| Show InChI InChI=1S/C25H25ClFN3O3S/c1-29-11-2-3-23(29)18-6-9-24(21(27)15-18)30-12-10-22(25(30)31)28-34(32,33)20-8-5-16-13-19(26)7-4-17(16)14-20/h4-9,13-15,22-23,28H,2-3,10-12H2,1H3/t22-,23?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrate				Bioorg Med Chem Lett 21: 1582-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.131 BindingDB Entry DOI: 10.7270/Q28052WG
					More data for this Ligand-Target Pair