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SMILES: O=c1[nH]c(nc2ccc(cc12)-c1cn[nH]c1)C1CCc2ccccc2O1

InChI Key: InChIKey=BKXGOGIYRRUAFL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338695   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 2


(Homo sapiens (Human))		BDBM50338695
PNG
(2-(chroman-2-yl)-6-(1H-pyrazol-4-yl)quinazolin-4(3...)
Show SMILES O=c1[nH]c(nc2ccc(cc12)-c1cn[nH]c1)C1CCc2ccccc2O1
Show InChI InChI=1S/C20H16N4O2/c25-20-15-9-13(14-10-21-22-11-14)5-7-16(15)23-19(24-20)18-8-6-12-3-1-2-4-17(12)26-18/h1-5,7,9-11,18H,6,8H2,(H,21,22)(H,23,24,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2n/an/an/an/an/an/a



Translational Research Institute

Curated by ChEMBL


Assay Description
Inhibition of ROCK2 by HTRF assay

Bioorg Med Chem Lett 21: 1844-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.039
BindingDB Entry DOI: 10.7270/Q20G3KFF
More data for this
Ligand-Target Pair