BDBM50339137 CHEMBL1323355::Dextromepromazine::Levomepromazine

SMILES: COc1ccc2Sc3ccccc3N(C[C@@H](C)CN(C)C)c2c1

InChI Key: InChIKey=VRQVVMDWGGWHTJ-AWEZNQCLSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50339137   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50339137 (CHEMBL1323355 | Dextromepromazine | Levomepromazin...) Show SMILES COc1ccc2Sc3ccccc3N(C[C@@H](C)CN(C)C)c2c1 Show InChI InChI=1S/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21/h5-11,14H,12-13H2,1-4H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation Curated by PDSP Ki Database									Brain Res 304: 1-7 (1984) Article DOI: 10.1016/0006-8993(84)90856-4 BindingDB Entry DOI: 10.7270/Q21N7ZMS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50339137 (CHEMBL1323355 | Dextromepromazine | Levomepromazin...) Show SMILES COc1ccc2Sc3ccccc3N(C[C@@H](C)CN(C)C)c2c1 Show InChI InChI=1S/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21/h5-11,14H,12-13H2,1-4H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
St, Marianna University School of Medicine Curated by PDSP Ki Database									Brain Res 402: 331-8 (1987) Article DOI: 10.1016/0006-8993(87)90040-0 BindingDB Entry DOI: 10.7270/Q2T43RMR
					More data for this Ligand-Target Pair
Pleiotropic ABC efflux transporter of multiple drugs (Saccharomyces cerevisiae S288c)	BDBM50339137 (CHEMBL1323355 | Dextromepromazine | Levomepromazin...) Show SMILES COc1ccc2Sc3ccccc3N(C[C@@H](C)CN(C)C)c2c1 Show InChI InChI=1S/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21/h5-11,14H,12-13H2,1-4H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw Medical University Curated by ChEMBL					Assay Description Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assay				Antimicrob Agents Chemother 53: 1516-27 (2009) Article DOI: 10.1128/AAC.00956-08 BindingDB Entry DOI: 10.7270/Q2125TNZ
					More data for this Ligand-Target Pair