BDBM50339179 (8S,11S,14S,17S,20S,23S,26S,29S)-26-((1H-imidazol-5-yl)methyl)-20-((1H-indol-3-yl)methyl)-29-((S)-2-((2S,3R)-2-((S)-2-acetamido-4-methylpentanamido)-3-hydroxybutanamido)-3-phenylpropanamido)-8-((S)-1-amino-3-hydroxy-1-oxopropan-2-ylcarbamoyl)-14-(3-amino-3-oxopropyl)-23-(4-hydroxybenzyl)-11-isobutyl-17-methyl-2,10,13,16,19,22,25,28-octaoxo-3,9,12,15,18,21,24,27-octaazadotriacontan-32-oic acid::CHEMBL1689411

SMILES: CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(C)=O)C(=O)N[C@@H](CO)C(N)=O

InChI Key: InChIKey=IWIUNJXEPOJENS-DTOIXECGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p53-Binding Protein HDMX (Homo sapiens (Human))	BDBM50339179 ((8S,11S,14S,17S,20S,23S,26S,29S)-26-((1H-imidazol-...) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(C)=O)C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C77H108N18O20/c1-40(2)30-56(85-45(8)99)76(114)95-65(43(6)97)77(115)93-59(32-46-16-10-9-11-17-46)73(111)88-55(26-28-64(102)103)70(108)92-61(35-49-37-80-39-83-49)75(113)90-58(33-47-21-23-50(100)24-22-47)74(112)91-60(34-48-36-82-52-19-13-12-18-51(48)52)71(109)84-42(5)67(105)86-54(25-27-63(78)101)69(107)89-57(31-41(3)4)72(110)87-53(20-14-15-29-81-44(7)98)68(106)94-62(38-96)66(79)104/h9-13,16-19,21-24,36-37,39-43,53-62,65,82,96-97,100H,14-15,20,25-35,38H2,1-8H3,(H2,78,101)(H2,79,104)(H,80,83)(H,81,98)(H,84,109)(H,85,99)(H,86,105)(H,87,110)(H,88,111)(H,89,107)(H,90,113)(H,91,112)(H,92,108)(H,93,115)(H,94,106)(H,95,114)(H,102,103)/t42-,43+,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,65-/m0/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...				Bioorg Med Chem Lett 21: 1472-5 (2011) Article DOI: 10.1016/j.bmcl.2011.01.004 BindingDB Entry DOI: 10.7270/Q2M32W33
					More data for this Ligand-Target Pair