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BDBM50339260 (Z/E)-3-(benzylthiomethylene)indolin-2-one::CHEMBL1689600

SMILES: O=C1Nc2ccccc2C1=CSCc1ccccc1

InChI Key: InChIKey=ZJCFRYXUSZVGBU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339260   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Falcipain-2


(Plasmodium falciparum)
BDBM50339260
PNG
((Z/E)-3-(benzylthiomethylene)indolin-2-one | CHEMB...)
Show SMILES O=C1Nc2ccccc2C1=CSCc1ccccc1 |w:10.12|
Show InChI InChI=1S/C16H13NOS/c18-16-14(13-8-4-5-9-15(13)17-16)11-19-10-12-6-2-1-3-7-12/h1-9,11H,10H2,(H,17,18)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Lisbon

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...


Eur J Med Chem 46: 927-33 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.008
BindingDB Entry DOI: 10.7270/Q2ZC8345
More data for this
Ligand-Target Pair