BDBM50339288 5-(3-Nitrophenyl)-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one::CHEMBL1689661

SMILES: [O-][N+](=O)c1cccc(c1)-c1cc(=O)n2[nH]c(c(-c3ccccc3)c2n1)C(F)(F)F

InChI Key: InChIKey=ZVFPZURJSMVIRT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv7.2/Kv7.3 (Homo sapiens (Human))	BDBM50339288 (5-(3-Nitrophenyl)-3-phenyl-2-(trifluoromethyl)pyra...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1cc(=O)n2[nH]c(c(-c3ccccc3)c2n1)C(F)(F)F Show InChI InChI=1S/C19H11F3N4O3/c20-19(21,22)17-16(11-5-2-1-3-6-11)18-23-14(10-15(27)25(18)24-17)12-7-4-8-13(9-12)26(28)29/h1-10,24H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
Hebei Medical University Curated by ChEMBL					Assay Description Activation of KCNQ2/Q3 expressed in CHO cells by atomic absorption Rb'+ efflux assay				Eur J Med Chem 46: 934-43 (2011) Article DOI: 10.1016/j.ejmech.2011.01.010 BindingDB Entry DOI: 10.7270/Q2TM7BDF
					More data for this Ligand-Target Pair