BDBM50339322 (5S,7R)-N-benzhydryl-5-phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide::CHEMBL1688102

SMILES: FC(F)(F)[C@H]1C[C@H](Nc2c(cnn12)C(=O)NC(c1ccccc1)c1ccccc1)c1ccccc1

InChI Key: InChIKey=DSZIJTUXGRIYIN-XZOQPEGZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50339322 ((5S,7R)-N-benzhydryl-5-phenyl-7-(trifluoromethyl)-...) Show SMILES FC(F)(F)[C@H]1C[C@H](Nc2c(cnn12)C(=O)NC(c1ccccc1)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C27H23F3N4O/c28-27(29,30)23-16-22(18-10-4-1-5-11-18)32-25-21(17-31-34(23)25)26(35)33-24(19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15,17,22-24,32H,16H2,(H,33,35)/t22-,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of CaSR expressed in CHO cells incubated with compound for 10 mins measured after 1 hr by [35S]GTPgammaS binding assay				J Med Chem 54: 1430-40 (2011) Article DOI: 10.1021/jm101452x BindingDB Entry DOI: 10.7270/Q2K35TZ9
					More data for this Ligand-Target Pair